iCASE Projects

Displaying 1 - 10 of 10

Master protocol trials for the development of oncology drugs

Supervisor: Dr David Robertson

Department/InstituteMRC Biostatistics Unit

Industrial Partner:IQVIA

Integrating genomic, multi-omic and clinical data at population scale to inform therapeutic targets and drug development programmes

Supervisor: Professor Adam Butterworth

Department/InstituteDepartment Public Health & Primary Care

Industrial Partner:AstraZeneca Centre for Genomics Research (CGR)

Designing self-assembling multi-functional biomolecular condensates to sense disease causing proteins in the cell and target them for degradation

Supervisor: Dr Janet Kumita, and Prof Laura Itzhaki

Department/InstituteDepartment of Pharmacology

Industrial Partner:Transition Bio

Uncovering novel negative regulators of T cell immunity to cancer

Supervisor: Dr Rahul Roychoudhuri

Department/InstituteDepartment of Pathology

Industrial Partner:AstraZeneca

Characterisation of antigenic targets involved in Chlamydia trachomatis infection identified by phenotypic phage display

Supervisor: Dr Richard Hayward

Department/InstituteDepartment of Pathology

Industrial Partner:AstraZeneca

Development and optimisation of LC-MS/MS based methods for plasma peptide and protein analysis

Supervisor: Dr Richard Kay

Department/InstituteInstitute of Metabolic Science

Industrial Partner:Drug Development Solutions Limited

Exploring peripheral actions of targeting GIPR

Supervisor: Professor Fiona Gribble

Department/InstituteInstitute of Metabolic Science

Industrial Partner:AstraZeneca

Using human genetics to identify neurodegenerative disorders likely to be alleviated by blocking SARM1

Supervisor: Professor Michael Coleman

Department/InstituteDepartment of Clinical Neurosciences

Industrial Partner:AstraZeneca

RF coils for human 11.7T metabolic MRI

Supervisor: Professor Chris Rodgers

Department/InstituteDepartment of Clinical Neurosciences

Industrial Partner:PulseTeq Limited

Phase transitions go viral: targeting viral replication through modulation of biomolecular condensates

Supervisor: Dr Alexander Borodavka

Department/InstituteDepartment of Biochemistry

Industrial Partner:Transition Bio